Reference:
Krauson, A. J., Casimero, F. V. C., Siddiquee, Z., & Stone, J. R. (2023). Duration of SARS-CoV-2 mRNA vaccine persistence and factors associated with cardiac involvement in
recently vaccinated patients. npj Vaccines, 8, 141. https://doi.org/10.1038/s41541-023-00742-7
Summary:
This study investigates the persistence of SARS-CoV-2 mRNA vaccines in human tissues, focusing on recently vaccinated patients. Autopsies revealed that vaccine mRNA was predominantly detected in axillary lymph nodes within 30 days post-vaccination but not in other tissues like the liver or spleen. Notably, vaccine mRNA was found in the myocardium of some patients, all of whom displayed healing myocardial injury before or at the time of vaccination. The presence of vaccine mRNA in cardiac tissues hints at potential implications for understanding vaccine-related myocarditis, although the study concludes that further research is essential to fully comprehend the biodistribution and persistence of these vaccines.