SAVIMS

SARS-CoV-2 mRNA Vaccination and Myocarditis in Adolescents

Reference:

Høeg, T. B., Krug, A., Stevenson, J., & Mandrola, J. (2021). SARS-CoV-2 mRNA vaccination-associated myocarditis in children ages 12-17: A stratified national database analysis. medRxiv. https://doi.org/10.1101/2021.08.30.21262866

Summary:

This study investigates the incidence of myocarditis in adolescents aged 12-17 following mRNA COVID-19 vaccinations. Using data from the Vaccine Adverse Event Reporting System (VAERS), the authors analysed reports from January to June 2021. They found that rates of cardiac adverse events (CAE) were significantly higher in boys aged 12-15 (162.2 per million) and 16-17 (94.0 per million) after the second dose compared to girls of the same age. The risk of post-vaccination myocarditis was notably greater than the hospitalization risk from COVID-19 for healthy boys without comorbidities. The findings suggest a need for ongoing research into the long-term effects of vaccination-related myocarditis and a careful consideration of the benefits and risks of vaccination in this demographic.

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