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Impact of Vaccination on SARS-CoV-2 Evolution

Reference:

Vanden Bossche, G. (2022). Poor virus-neutralizing capacity in highly C-19 vaccinated populations could soon lead to a fulminant spread of SARS-CoV-2 super variants that are highly infectious and highly virulent in vaccinees while being fully resistant to all existing and future spike-based C-19 vaccines.

Summary:

In his article, Vanden Bossche (2022) raises concerns about the potential consequences of mass COVID-19 vaccination. He argues that poor neutralising capacity in highly vaccinated populations may lead to the emergence of highly infectious and virulent SARS-CoV-2 variants that evade existing vaccines. The focus on spike protein-targeted antibodies may inadvertently enhance the virus’s ability to infect vaccinated individuals, while their innate immune responses weaken over time. He suggests that ongoing immune pressure from vaccination is driving the evolution of new variants, which could result in increased disease severity among vaccinated individuals. The article further posits that without a shift from vaccination to antiviral chemoprophylaxis, the pandemic may escalate, with significant morbidity and mortality risks for vaccinated populations. Vanden Bossche urges public health authorities to reassess their strategies to mitigate these evolving threats effectively.

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