Reference:
Faksova, K., Walsh, D., Jiang, Y., Griffin, J., Phillips, A., Gentile, A., … & Hviid, A. (2024). COVID-19 vaccines and adverse events of special interest: A multinational Global Vaccine Data Network (GVDN) cohort study of 99 million vaccinated individuals. Vaccine. https://doi.org/10.1016/j.vaccine.2024.01.100
Summary:
This study evaluates the risk of adverse events following COVID-19 vaccination across 99 million individuals in eight countries. Using a common protocol, the researchers compared observed rates of 13 adverse events of special interest (AESI) against expected rates derived from pre-vaccination data. Significant findings included elevated risks for Guillain-Barré syndrome and cerebral venous sinus thrombosis after the ChAdOx1 vaccine, and myocarditis and pericarditis post mRNA vaccines BNT162b2 and mRNA-1273. The study highlights the importance of ongoing vaccine safety monitoring and identifies potential safety signals, warranting further investigation into the rare adverse events associated with COVID-19 immunisation.