Reference:
Kamber Zaidi, A., & Dehgani-Mobaraki, P. (2021). The mechanisms of action of Ivermectin against SARS-CoV-2: An evidence-based clinical review article. The Journal of Antibiotics, 74(7), 441-454. https://doi.org/10.1038/s41429-021-00430-5
Summary:
This review article examines the potential of Ivermectin as a therapeutic agent against SARS-CoV-2 amidst the COVID-19 pandemic. It highlights Ivermectin’s mechanism of action, including its ability to inhibit viral entry and replication by targeting various cellular pathways. The authors summarise evidence from numerous studies, suggesting significant improvements in outcomes for COVID-19 patients treated with Ivermectin. Despite some conflicting clinical trial results, the article emphasizes the drug’s antiviral properties and its potential role in managing COVID-19 complications. The findings suggest that Ivermectin could serve as a valuable option, particularly in regions with limited access to vaccines or other treatments. The review also underscores the importance of further research to establish clear guidelines for its use.